High-resolution electrophysiology on a chip: Transient dynamics of alamethicin channel formation

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High-resolution electrophysiology on a chip: Transient dynamics of alamethicin channel formation.

Microstructured planar substrates have been shown to be suitable for patch clamp recording from both whole cells and isolated patches of membrane, as well as for measurements from planar lipid bilayers. Here, we further explore this technology with respect to high-resolution, low noise single-channel recording. Using solvent-free lipid bilayers from giant unilamellar vesicles obtained by electr...

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ژورنال

عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Biomembranes

سال: 2006

ISSN: 0005-2736

DOI: 10.1016/j.bbamem.2006.03.023